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OCR: usually of The secretion from pituitary adenomas mixed cell GH alone, but the tumour may also be o atients are types and thirty per cent of acromegalic lly GH andalso hyperprolactinaemic. Very occasion 11. GH cell prolactin may originate from the same c sely adenomas occur in both sparsely and der milar to granulated forms. The latter look very si with acid na in the normal somatotrophs and the cells stain dyes, representing the eosinophil adeno he sparselyconventional classification. By contrast, ents the parsely granulated somatotroph adenoma repres chromophobe adenoma. Clinically, the s tion and to be more granulated somatotroph adenomas tend aggressive, the cells show less differentia je tumour more invasive